Aims: Leptin plays an important role in the pathogenesis of obesity and diabetes. yet the regulatory mechanisms of this hormone have not been fully elucidated. In this study. we aimed to clarify the roles of insulin and glucose in leptin secretion and mRNA production using inhibitors of insulin signal transduction in adipocytes cultured under glucose-free or normal conditions. https://yeswellneses.shop/product-category/vitamins-a/