The ACURATE neo transcatheter aortic valve is a self-expanding device suitable for both transfemoral and transapical approach. but specific groups of patients are under-represented in clinical trials. We aim to provide a comprehensive systematic review on TAVI with ACURATE neo in those special populations. TAVI in bicuspid aortic valve. https://www.herbsdailyes.shop/product-category/throat-support/